Epithelial and endothelial cells can form selective barriers between tissues and different body compartments. They polarize and adhere to each other through intercellular complexes including tight junctions ( TJs), adherens junctions and desmosomes.
上皮细胞和内皮细胞在组织和不同的细胞间形成了选择性的屏障,它们发生了极化,且通过细胞间的复合物互相连接,这些复合物包括紧密连接、粘性连接和桥粒。
Aprotinin could downgrade the expression of ICAM-1 of TNF α activating endothelial cells and prevent the loss of β-catenin of the cells, protect the adherens junctions of endothelials cells.
抑肽酶可抑制TNFα活化的人脐静脉内皮细胞ICAM-1的表达,可避免β-catenin的丢失。
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